Use of immunoassays for biomonitoring of herbicide metabolites in urine

被引:15
作者
Mastin, JP
Striley, CAF
Biagini, RE
Hines, CJ
Hull, RD
MacKenzie, BA
Robertson, SK
机构
[1] NIOSH, Div Biomed & Behav Sci, Cincinnati, OH 45223 USA
[2] NIOSH, Div Surveillance Hazard Evaluat & Field Studies, Cincinnati, OH 45223 USA
关键词
biological monitoring; immunoassay; atrazine; metolachlor; urine; metabolites;
D O I
10.1016/S0003-2670(98)00451-6
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Commercially available ground-water immunoassays (RaPID Assay(R)) are being evaluated to determine their potential value for measuring herbicides or their metabolites in urine. Preliminary investigations of matrix effects and cross-reactivities indicate potential usefulness for the atrazine kit, but not the metolachlor kit, as a urinary biomonitoring tool. (C) 1998 Published by Elsevier Science B.V. All rights reserved.
引用
收藏
页码:119 / 124
页数:6
相关论文
共 8 条
  • [1] BIAGINI RE, 1995, B ENVIRON CONTAM TOX, V54, P245
  • [2] Biagini RE, 1996, ACS SYM SER, V646, P286
  • [3] BLADEREN PJ, 1980, EUR J MED CHEM, V15, P495
  • [4] Identification of a major human urinary metabolite of metolachlor by LC-MS/MS
    Driskell, WJ
    Hill, RH
    [J]. BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, 1997, 58 (06) : 929 - 933
  • [5] DETERMINATION OF ATRAZINE AND ALACHLOR IN NATURAL-WATERS BY A RAPID-MAGNETIC PARTICLE-BASED ELISA - INFLUENCE OF COMMON CROSS-REACTANTS - DEETHYLATRAZINE, DEISOPROPYLATRAZINE, SIMAZINE AND METOLACHLOR
    GASCON, J
    MARTINEZ, E
    BARCELO, D
    [J]. ANALYTICA CHIMICA ACTA, 1995, 311 (03) : 357 - 364
  • [6] Determination of trace atrazine levels in water by a sensitive magnetic particle-based enzyme immunoassay
    Hottenstein, CS
    Rubio, FM
    Herzog, DP
    Fleeker, JR
    Lawruk, TS
    [J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1996, 44 (11) : 3576 - 3581
  • [7] DETERMINATION OF ATRAZINE METABOLITES IN HUMAN URINE - DEVELOPMENT OF A BIOMARKER OF EXPOSURE
    LUCAS, AD
    JONES, AD
    GOODROW, MH
    SAIZ, SG
    BLEWETT, C
    SEIBER, JN
    HAMMOCK, BD
    [J]. CHEMICAL RESEARCH IN TOXICOLOGY, 1993, 6 (01) : 107 - 116
  • [8] BIOLOGICAL MONITORING OF COMMERCIAL PESTICIDE APPLICATORS FOR URINE METABOLITES OF THE HERBICIDE ALACHLOR
    SANDERSON, WT
    BIAGINI, R
    TOLOS, W
    HENNINGSEN, G
    MACKENZIE, B
    [J]. AMERICAN INDUSTRIAL HYGIENE ASSOCIATION JOURNAL, 1995, 56 (09): : 883 - 889