Interrupted nazarov cyclization on silica gel

被引：59

作者：

Dhoro, F ^{[1
]}

Tius, MA ^{[1
]}

机构：

[1] Univ Hawaii, Dept Chem, Honolulu, HI 96822 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2005年 / 127卷 / 36期

关键词：

D O I：

10.1021/ja053393g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Exposure of a mixture of propargyl vinyl ketone and a nucleophilic primary or secondary amine to activated dry silica gel in the absence of solvent leads to a cascade of reactions that results in the formation of an aminocyclopentenone. The reaction with triethylamine leads to a cross-conjugated cyclopentadienone. Copyright © 2005 American Chemical Society.

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页码：12472 / 12473

页数：2

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