Interactions between platelets and leukocytes during hemodialysis

被引：16

作者：

Bonomini, M ^{[1
]}

Sirolli, V ^{[1
]}

Stuard, S ^{[1
]}

Settefrati, N ^{[1
]}

机构：

[1] Gabriele Dannunzio Univ, Inst Nephrol, Dept Med, Chieti, Italy

来源：

ARTIFICIAL ORGANS | 1999年 / 23卷 / 01期

关键词：

biocompatibility; hemodialysis membrane; platelets; leukocytes; platelet-leukocyte interactions; reactive oxygen species;

D O I：

10.1046/j.1525-1594.1999.06271.x

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

The formation of platelet-leukocyte microaggregates has been observed in a variety of conditions. When platelets and leukocytes coaggregate, in general, a reciprocal activation occurs when both cells are activated, and the interactions between activated platelets and leukocytes may be relevant in both hemostasis and inflammatory processes. The study of platelet-leukocyte interactions in hemodialysis offers the novel aspect of cellular-cellular interaction as a new parameter for evaluating the biocompatibility of dialyzer membranes. This article reviews the investigations of the interactions between platelets and leukocytes during hemodialysis and the pathophysiologic implications which may stem from such interactions.

引用

页码：23 / 28

页数：6

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