Effect of albumen as protein-based foaming agent in a calcium phosphate bone cement

被引：10

作者：

Almirall, A ^{[1
]}

Delgado, JA ^{[1
]}

Ginebra, MP ^{[1
]}

Planell, JA ^{[1
]}

机构：

[1] Tech Univ Catalonia, Dept Mat Sci & Met, Biomat Div, Res Ctr Biomed Engn, Barcelona 08028, Spain

来源：

BIOCERAMICS 16 | 2004年 / 254-2卷

关键词：

calcium phosphate cement; macroporosity; injectable bone graft; foams; scaffolds;

D O I：

10.4028/www.scientific.net/KEM.254-256.253

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 [生物医学工程];

摘要：

In this work, the preparation and characterization of a macroporous alpha-tricalcium phosphate (alpha-TCP) cement with albumen as foaming agent is discussed. X-ray diffraction (XRD) and infrared (IR) analysis of the samples reveal that the conversion of alpha-TCP to calcium deficient hydroxyapatite (CDHA) was not affected by the addition of albumen in the cement paste. SEM observations showed the formation of spherical macropores with diameters between 100 and 500 mum. The use of phosphate solutions, which have an accelerating effect of the setting reaction, influenced the foam stability, reducing the macroporosity of the set cements.

引用

页码：253 / 256

页数：4

共 10 条

[1]

Preparation of macroporous calcium phosphate cement tissue engineering scaffold [J].

Barralet, JE ;

Grover, L ;

Gaunt, T ;

Wright, AJ ;

Gibson, IR .

BIOMATERIALS, 2002, 23 (15) :3063-3072

[2]

CONSTANTZ BR, 1998, J BIOMED MATER RES B, V43, P428

[3]

Setting reaction and hardening of an apatitic calcium phosphate cement [J].

Ginebra, MP ;

Fernandez, E ;

DeMaeyer, EAP ;

Verbeeck, RMH ;

Boltong, MG ;

Ginebra, J ;

Driessens, FCM ;

Planell, JA .

JOURNAL OF DENTAL RESEARCH, 1997, 76 (04) :905-912

[4]

GINEBRA MP, 1997, THESIS U POLITECNICA

[5]

Ginebra MP, 1998, BIOCERAMICS, V11, P243

[6]

Formation of macropores in calcium phosphate cements through the use of mannitol crystals [J].

Markovic, M ;

Takagi, S ;

Chow, LC .

BIOCERAMICS, 2000, 192-1 :773-776

[7]

Histological evaluation of the bone response to calcium phosphate cement implanted in cortical bone [J].

Ooms, EM ;

Wolke, JGC ;

van de Heuvel, MT ;

Jeschke, B ;

Jansen, JA .

BIOMATERIALS, 2003, 24 (06) :989-1000

[8]

Influence of surfactant molecules as air-entraining agent for bone cement macroporosity [J].

Sarda, S ;

Nilsson, M ;

Balcells, M ;

Fernández, E .

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2003, 65A (02) :215-221

[9]

Formation of macropores in calcium phosphate cement implants [J].

Takagi, S ;

Chow, LC .

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2001, 12 (02) :135-139

[10]

Zayas J.F., 1997, FUNTIONALITY PROTEIN

← 1 →