Miniaturization in functional genomics and proteomics

被引：100

作者：

Sauer, S ^{[1
]}

Lange, BMH ^{[1
]}

Gobom, J ^{[1
]}

Nyarsik, L ^{[1
]}

Seitz, H ^{[1
]}

Lehrach, H ^{[1
]}

机构：

[1] Max Planck Inst Mol Genet, Dept Vertebrate Genom, D-14195 Berlin, Germany

来源：

NATURE REVIEWS GENETICS | 2005年 / 6卷 / 06期

关键词：

D O I：

10.1038/nrg1618

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Proteins are the key components of the cellular machinery responsible for processing changes that are ordered by genomic information. Analysis of most human proteins and nucleic acids is important in order to decode the complex networks that are likely to underlie many common diseases. Significant improvements in current technology are also required to dissect the regulatory processes in high-throughtput and with low cost. Miniaturization of biological assays is an important prerequisite to achieve these goals in the near future.

引用

页码：465 / 476

页数：12

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