Effects of a multidisciplinary inpatient intervention on body composition, aerobic fitness, and quality of life in severely obese girls and boys

Purpose: The last few decades have seen a major increase in the prevalence of juvenile obesity. Inpatient treatment programs are used mainly in children with severe obesity and related comorbidities. The aim of this study was to evaluate the gender differences of an 8-week multidisciplinary inpatient program on body weight, body composition, aerobic fitness, and quality of life of severely obese children and adolescents. Methods: Body weight was measured daily, and body composition, aerobic fitness, and quality of life were measured at the beginning and the end of an 8-week multidisciplinary inpatient program in 130 severely obese patients (52 girls, 78 boys), median (25th, 75th percentile) age of 13.8 (12.1, 15.0) years, median body weight of 89.4 kg (77.1, 100.1), and a body mass index of 33.4 (30.1, 36.6) kg/m(2), which is well above the 98th percentile. The inpatient program was based on a multidisciplinary treatment and education program that focused on daily physical activity, a 1200-1600 kcal/day balanced nutrition regimen, and a behavior modification therapy. Results: All results are expressed as medians (25th, 75th percentiles). At the end of the program all patients had lost a significant amount of body weight: 12.7 kg (10.8, 16.6), p <.001, girls 11.6 kg (9.7, 13.2), boys 13.7 kg (11.7, 17.3), p <.001, absolute body fat 8.0 kg (6.8, 10.0) p < 001, girls 7.0 kg (5.7, 8.1), boys 9.4 kg (7.6, 11.0) p, <.001, % body fat per kg body weight: 4.9% (3.2, 6.6) p <.001, girls 3.7% (2.7, 4.9), boys 5.7% (4.0, 7.5) p <.001, and absolute fat free (or lean body) mass: 1.8 kg (0.64, 3.0) p <.001, girls 1.8 kg (0.87, 3.2), boys 1.7 kg (0.50, 2.9) p =.43. In addition, all measurements of aerobic fitness: VO(2)peak (mL/min - kg) and peak mechanical power (watts and watt/kg) and of quality of life increased significantly (p <.001, p <.001, p <.004 to p <.001). Conclusion: A multidisciplinary inpatient treatment program including moderate calorie restriction, daily physical activity, and behavior modification induced a major weight loss, a decrease in body fat, and an increse in aerobic fitness as well as the quality fo life of severely obese children and adolescents. Weight loss and the decrease in body fat (absolute and percent) were significantly more pronounced in boys than girls. (C) 2008 Society for Adolescent Medicine. All rights reserved.