Critical features of FAK-expressing AML bone marrow microenvironment through leukemia stem cell hijacking of mesenchymal stromal cells

被引:22
作者
Despeaux, M. [1 ,2 ,3 ]
Labat, E. [4 ,5 ,6 ]
Gadelorge, M. [4 ,5 ,6 ]
Prade, N. [7 ]
Bertrand, J. [1 ,2 ,3 ]
Demur, C. [7 ,8 ]
Recher, C. [7 ,8 ]
Bonnevialle, P. [9 ]
Payrastre, B. [8 ,10 ]
Bourin, P. [4 ,5 ,6 ]
Racaud-Sultan, C. [1 ,2 ,3 ]
机构
[1] Fac Med Toulouse, INSERM, U1043, F-31073 Toulouse, France
[2] CNRS, U5282, Toulouse, France
[3] Univ Toulouse, UPS, Ctr Physiopathol Toulouse Purpan CPTP, Toulouse, France
[4] EFS PM, Lab Therapie Cellulaire, Toulouse, France
[5] STROMALab UMR UPS CNRS EFS 5273, Toulouse, France
[6] Fac Med Toulouse, INSERM, U1031, F-31073 Toulouse, France
[7] Univ Toulouse, Ctr Rech Cancerol Toulouse, INSERM, CNRS,UMR 1037,ERL 5294, Toulouse, France
[8] CHU Purpan, Serv Clin & Lab Hematol, Toulouse, France
[9] CHU Purpan, Serv Clin Chirurg Orthoped & Traumatol, Toulouse, France
[10] Fac Med Toulouse, INSERM, Inst Malad Metab & Cardiovasc, U1048, F-31073 Toulouse, France
关键词
ACUTE MYELOID-LEUKEMIA; POOR-PROGNOSIS; NICHE;
D O I
10.1038/leu.2011.145
中图分类号
R73 [肿瘤学];
学科分类号
100214 [肿瘤学];
摘要
引用
收藏
页码:1789 / 1793
页数:5
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