Low concentrations of nitric oxide exert a hormetic effect on Mycobacterium tuberculosis in vitro

被引：16

作者：

Brugmann, WB ^{[1
]}

Firmani, MA ^{[1
]}

机构：

[1] Louisiana State Univ, Hlth Sci Ctr, Sch Allied Hlth Profess, Dept Clin Lab Sci, New Orleans, LA 70112 USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2005年 / 43卷 / 09期

关键词：

D O I：

10.1128/JCM.43.9.4844-4846.2005

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Susceptibilities of 12 clinical Mycobacterium tuberculosis isolates to acidified sodium nitrite (ASN) were compared. The results demonstrate that 8 of the 12 isolates exhibited enhanced survival levels in 1.5 mM ASN compared to levels in medium alone, suggesting that low concentrations of reactive nitrogen intermediates have a hormetic effect on M. tuberculosis in vitro.

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页码：4844 / 4846

页数：3

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