PAK'n it in: Identification of a selective PAK inhibitor

被引：7

作者：

Bokoch, Gary M. ^{[1
]}

机构：

[1] Scripps Res Inst, Dept Cell Biol, La Jolla, CA 92037 USA

来源：

CHEMISTRY & BIOLOGY | 2008年 / 15卷 / 04期

关键词：

D O I：

10.1016/j.chembiol.2008.03.011

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

p21-activated kinases are important signaling kinases for which no specific chemical inhibitors are known. In this issue of Chemistry & Biology, Deacon et al. target allosteric transitions undergone during PAK activation to identify a selective inhibitor (Deacon et al., 2008).

引用

页码：305 / 306

页数：2

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