A novel optically based chemosensor for the detection of blood Na+

被引：74

作者：

Gunnlaugsson, T ^{[1
]}

Nieuwenhuyzen, M

Richard, L

Thoss, V

机构：

[1] Univ Dublin Trinity Coll, Dept Chem, Dublin 2, Ireland

[2] Queens Univ Belfast, Sch Chem, Belfast BT9 5AG, Antrim, North Ireland

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 28期

关键词：

D O I：

10.1016/S0040-4039(01)00823-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The azo dye based chemosensor 2 displays extremely good sensitivity acid selectivity for Na+ over other physiologically important alkali and alkali earth metal ions in the 0.3 1.0 x 10(-4) M concentration range as well as being pH independent above pH 3.9. This sensitivity coincides with the Na+ concentration range found in blood. Thr sensor exhibits almost 110 nm hypsochromic shift in the absorption spectrum upon Na+ detection, with a strong colour change from red to yellow in aqueous solution which is clearly visible to the naked eye even at low concentrations. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：4725 / 4728

页数：4

共 30 条

[1] MEASUREMENT OF CA-2+ CONCENTRATIONS IN LIVING CELLS [J].

BLINKS, JR ;

WIER, WG ;

HESS, P ;

PRENDERGAST, FG .

PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, 1982, 40 (1-2) :1-114

[2]

*BRUK AN XRAY SYST, 1998, SMART SOFTW REF MAN

[3]

Czarnik A.W., 1993, INSTRUM SCI TECHNOL, DOI DOI 10.1080/10739149408001201

[4] CHEMICAL COMMUNICATION IN WATER USING FLUORESCENT CHEMOSENSORS [J].

CZARNIK, AW .

ACCOUNTS OF CHEMICAL RESEARCH, 1994, 27 (10) :302-308

[5] Combining luminescence, coordination and electron transfer for signalling purposes [J].

de Silva, AP ;

Fox, DB ;

Huxley, AJM ;

Moody, TS .

COORDINATION CHEMISTRY REVIEWS, 2000, 205 :41-57

[6] Fluorescent switches with high selectivity towards sodium ions: Correlation of ion-induced conformation switching with fluorescence function [J].

de Silva, AP ;

Gunaratne, HQN ;

Gunnlaugsson, T ;

Nieuwenhuizen, M .

CHEMICAL COMMUNICATIONS, 1996, (16) :1967-1968

[7] Signaling recognition events with fluorescent sensors and switches [J].

de Silva, AP ;

Gunaratne, HQN ;

Gunnlaugsson, T ;

Huxley, AJM ;

McCoy, CP ;

Rademacher, JT ;

Rice, TE .

CHEMICAL REVIEWS, 1997, 97 (05) :1515-1566

[8]

Desvergne J.-P., 1997, CHEMOSENSORS ION MOL

[9] ION-SELECTIVE CROWN ETHER DYES [J].

DIX, JP ;

VOGTLE, F .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1978, 17 (11) :857-858

[10] LIGAND STRUCTURE AND COMPLEXATION .50. ION-SELECTIVE CROWN ETHER DYES [J].

DIX, JP ;

VOGTLE, F .

CHEMISCHE BERICHTE-RECUEIL, 1980, 113 (02) :457-470

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