The complete sequence of the mitochondrial genome of Saccharomyces cerevisiae

被引：339

作者：

Foury, F ^{[1
]}

Roganti, T ^{[1
]}

Lecrenier, N ^{[1
]}

Purnelle, B ^{[1
]}

机构：

[1] Unite Biochim Physiol, B-1348 Louvain, Belgium

来源：

FEBS LETTERS | 1998年 / 440卷 / 03期

关键词：

Saccharomyces cerevisiae; mitochondrial DNA; sequence; polymorphism;

D O I：

10.1016/S0014-5793(98)01467-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The currently available yeast mitochondrial DNA (mtDNA) sequence is incomplete, contains many errors and is derived from several polymorphic strains, Here, we report that the mtDNA sequence of the strain used for nuclear genome sequencing assembles into a circular map of 85779 bp which includes 10 kb of new sequence. We give a list of seven small hypothetical open reading frames (ORFs). Hot spots of point mutations are found in exons near the insertion sites of optional mobile group I intron-related sequences. Our data suggest that shuffling of mobile elements plays an important role in the remodelling of the yeast mitochondrial genome. (C) 1998 Federation of European Biochemical Societies.

引用

页码：325 / 331

页数：7

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