The mouse genome database (MGD): genetic and genomic information about the laboratory mouse

被引:42
作者
Blake, JA [1 ]
Richardson, JE [1 ]
Davisson, MT [1 ]
Eppig, JT [1 ]
机构
[1] Jackson Lab, Bar Harbor, ME 04609 USA
关键词
D O I
10.1093/nar/27.1.95
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The Mouse Genome Database (MGD) focuses on the integration of mapping, homology, polymorphism and molecular data about the laboratory mouse. Detailed descriptions of genes including their chromosomal location, gene function, disease associations, mutant phenotypes, molecular polymorphisms and links to representative sequences including ESTs are integrated within MGD, The association of information from experiment to gene to genome requires careful coordination and implementation of standardized vocabularies, unique nomenclature constructions, and detailed information derived from multiple sources. This information is linked to other public databases that focus on additional information such as expression patterns, sequences, bibliographic details and large mapping panel data. Scientists participate in the curation of MGD data by generating the Chromosome Committee Reports, consulting on gene family nomenclature revisions, and providing descriptions of mouse strain characteristics and of new mutant phenotypes, MGD is accessible at http://www.informatics.jax.org.
引用
收藏
页码:95 / 98
页数:4
相关论文
共 5 条
  • [1] The Mouse Genome Database (MGD), a comprehensive public resource of genetic, phenotypic and genomic data
    Blake, JA
    Richardson, JE
    Davisson, MT
    Eppig, JT
    Battles, J
    Begley, D
    Blackburn, R
    Bradt, D
    Colby, G
    Corbani, L
    Davis, G
    Doolittle, D
    Drake, T
    Frazer, K
    Gilbert, J
    Grant, P
    LennonPierce, M
    Maltais, L
    May, M
    McIntire, M
    Merriam, J
    Ormsby, J
    Palazola, R
    Ringwald, M
    Rockwood, S
    Sharpe, S
    Shaw, D
    Reed, D
    StanleyWalls, M
    Taylor, L
    [J]. NUCLEIC ACIDS RESEARCH, 1997, 25 (01) : 85 - 91
  • [2] The Mouse Genome Database (MGD): a community resource. Status and enhancements
    Blake, JA
    Eppig, JT
    Richardson, JE
    Davisson, MT
    [J]. NUCLEIC ACIDS RESEARCH, 1998, 26 (01) : 130 - 137
  • [3] Electronic access to mouse tumor data: the mouse tumor biology database (MTB) project
    Bult, CJ
    Krupke, DM
    Eppig, JT
    [J]. NUCLEIC ACIDS RESEARCH, 1999, 27 (01) : 99 - 105
  • [4] Informatics for mouse genetics and genome mapping
    Eppig, JT
    Blake, JA
    Davisson, MT
    Richardson, JE
    [J]. METHODS-A COMPANION TO METHODS IN ENZYMOLOGY, 1998, 14 (02): : 179 - 190
  • [5] GXD: a gene expression database for the laboratory mouse
    Ringwald, M
    Mangan, ME
    Eppig, JT
    Kadin, JA
    Richardson, JE
    [J]. NUCLEIC ACIDS RESEARCH, 1999, 27 (01) : 106 - 112