Efficient tautomerization hydrazone-azomethine imine under microwave irradiation.: Synthesis of [4,3′] and [5,3′]bipyrazoles

被引：75

作者：

Arrieta, A

Carrillo, JR

Cossío, FP

Díaz-Ortiz, A

Gómez-Escalonilla, MJ

de la Hoz, A

Langa, F

Moreno, A

机构：

[1] Univ Basque Country, Fac Quim, E-20080 San Sebastian, Spain

[2] Univ Castilla La Mancha, Fac Quim, E-13071 Ciudad Real, Spain

[3] Univ Castilla La Mancha, Fac Quim, Secc Toledo, E-45001 Toledo, Spain

来源：

TETRAHEDRON | 1998年 / 54卷 / 43期

关键词：

D O I：

10.1016/S0040-4020(98)00798-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Microwave irradiation induces the thermal isomerization of pyrazolyl hydrazones to the corresponding azomethine imines which undergo 1,3-dipolar cycloaddition with electron-poor dipolarophiles in a few min with good yields. By classical heating, several dipolarophiles do not react in comparable reaction conditions. Regiochemistry of bipyrazoles obtained from unsymmetrical dipolarophiles has been inferred by spectroscopic experiments. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：13167 / 13180

页数：14

共 37 条

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