High-Dose Intravenous Immunoglobulin as a Therapeutic Option for Deteriorating Patients With Coronavirus Disease 2019

被引：280

作者：

Cao, Wei ^{[1
]}

Liu, Xiaosheng ^{[2
]}

Bai, Tao ^{[3
]}

Fan, Hongwei ^{[1
]}

Hong, Ke ^{[3
]}

Song, Hui ^{[3
]}

Han, Yang ^{[1
]}

Lin, Ling ^{[1
]}

Ruan, Lianguo ^{[3
]}

Li, Taisheng ^{[1
]}

机构：

[1] Chinese Acad Med Sci, Peking Union Med Coll Hosp, Dept Infect Dis, 1 Shuai Fu Yuan, Beijing 100730, Peoples R China

[2] Tsinghua Univ, Sch Med, Tsinghua Peking Ctr Life Sci, Beijing, Peoples R China

[3] Jin Yin Tan Hosp, Dept Infect Dis, Wuhan, Peoples R China

来源：

OPEN FORUM INFECTIOUS DISEASES | 2020年 / 7卷 / 03期

关键词：

coronavirus disease 2019; high-dose intravenous immunoglobulin; immunomodulation; SARS-CoV-2; AUTOIMMUNE; OUTCOMES;

D O I：

10.1093/ofid/ofaa102

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The outbreak of coronavirus disease 2019 (COVID-19) has spread rapidly in China. Until now, no definite effective treatment has been identified. We reported on 3 patients with severe COV1D-19 who received high-dose intravenous immunoglobulin (IVIg) with satisfactory recovery. Based on these observations, randomized studies of high-dose IVIg should be considered in deteriorating patients infected with COVID-19. The outbreak of coronavirus disease 2019 (COVID-19) has spread rapidly in China. Until now, no definite effective treatment has been identified. We reported on 3 patients with severe COVID-19 who received high-dose intravenous immunoglobulin (IVIg) with satisfactory recovery. Based on these observations, randomized studies of high-dose IVIg should be considered in deteriorating patients infected with COVID-19.

引用

页码：1 / 6

页数：6

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