A clinical trial protocol for second line treatment of malignant brain tumors with BNCT at University of Tsukuba

被引:20
作者
Aiyama, H. [1 ]
Nakai, K. [1 ]
Yamamoto, T. [1 ,2 ]
Nariai, T. [3 ]
Kumada, H. [2 ]
Ishikawa, E. [1 ]
Isobe, T. [2 ]
Endo, K. [1 ]
Takada, T. [1 ]
Yoshida, F. [1 ]
Shibata, Y. [1 ]
Matsumura, A. [1 ]
机构
[1] Univ Tsukuba, Grad Sch Comprehens Human Sci, Dept Neurosurg, Tsukuba, Ibaraki, Japan
[2] Univ Tsukuba, Grad Sch Comprehens Human Sci, Dept Radiat Oncol, Tsukuba, Ibaraki, Japan
[3] Tokyo Med & Dent Univ, Dept Neurosurg, Bunkyouku, Japan
关键词
BNCT; Recurrent glioma; Recurrent malignant brain tumor;
D O I
10.1016/j.apradiso.2011.04.031
中图分类号
O61 [无机化学];
学科分类号
070301 [无机化学];
摘要
We have evaluated the efficacy and safety of boron neutron capture therapy (BNCT) for recurrent glioma and malignant brain tumor using a new protocol. One of the two patients enrolled in this trial is a man with recurrent glioblastoma and the other is a woman with anaplastic meningioma. Both are still alive and no severe adverse events have been observed. Our findings suggest that NCT will be safe as a palliative therapy for malignant brain tumors. (C) 2011 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1819 / 1822
页数:4
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