Arterial smooth muscle cell proliferation on a novel biomimicking, biodegradable vascular graft scaffold

被引：100

作者：

Stitzel, JD

Pawlowski, KJ

Wnek, GE

Simpson, DG

Bowlin, GL

机构：

[1] Virginia Commonwealth Univ, Dept Biomed Engn, Richmond, VA 23298 USA

[2] Virginia Commonwealth Univ, Dept Chem Engn, Richmond, VA 23298 USA

[3] Virginia Commonwealth Univ, Dept Anat, Richmond, VA 23298 USA

来源：

JOURNAL OF BIOMATERIALS APPLICATIONS | 2001年 / 16卷 / 01期

关键词：

D O I：

10.1106/U2UU-M9QH-Y0BB-5GYL

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

A study was conducted to create a biomimicking graft scaffold with collagen fibers for a reinforcement material and a biodegradable matrix material (composite structure). Collagen fibers were spun and a biodegradable PLA matrix was spun around this fiber for smooth muscle cell (SMC) seeding and to hold the fibers in place during tissue regeneration. The construct was seeded with human aortic SMCs and the resulting graft was analyzed. © 2001 Technomic Publishing Co., Inc.

引用

页码：22 / 33

页数：12

共 13 条

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