Epstein-Barr virus-associated hemophagocytic syndrome in a patient with lupus nephritis

被引：9

作者：

Isome, M ^{[1
]}

Suzuki, J ^{[1
]}

Takahashi, A ^{[1
]}

Murai, H ^{[1
]}

Nozawa, R ^{[1
]}

Suzuki, S ^{[1
]}

Kawasaki, Y ^{[1
]}

Suzuki, H ^{[1
]}

机构：

[1] Fukushima Med Univ, Sch Med, Dept Pediat, Fukushima 9601295, Japan

来源：

PEDIATRIC NEPHROLOGY | 2005年 / 20卷 / 02期

关键词：

Epstein-Barr virus; hemophagocytic syndrome; systemic lupus erythematosus; lupus nephritis; reactivation;

D O I：

10.1007/s00467-004-1704-9

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Hemophagocytic syndrome (HPS) is an unusual but severe illness associated with a variety of infections, as well as genetic, malignant tumors, and autoimmune diseases. We report an 11-year-old girl with systemic lupus erythematosus and nephritis who developed HPS associated with Epstein-Barr virus reactivation. In our patient, the onset of reactive HPS might be related to immunosuppressive treatment during the course of lupus nephritis.

引用

页码：226 / 228

页数：3

共 10 条

[1] Hemophagocytic syndromes and infection [J].

Fisman, DN .

EMERGING INFECTIOUS DISEASES, 2000, 6 (06) :601-608

[2] HIGH-DOSE GAMMA-GLOBULIN THERAPY IN THE REACTIVE HEMOPHAGOCYTIC SYNDROME [J].

GILL, DS ;

SPENCER, A ;

COBCROFT, RG .

BRITISH JOURNAL OF HAEMATOLOGY, 1994, 88 (01) :204-206

[3] HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS, INTERFERON-GAMMA-NAEMIA AND EPSTEIN-BARR-VIRUS INVOLVEMENT [J].

IMASHUKU, S ;

HIBI, S ;

FUJIWARA, F ;

IKUSHIMA, S ;

TODO, S .

BRITISH JOURNAL OF HAEMATOLOGY, 1994, 88 (03) :656-658

[4] Infection- and malignancy-associated hemophagocytic syndromes - Secondary hemophagocytic lymphohistiocytosis [J].

Janka, G ;

Imashuku, S ;

Elinder, G ;

Schneider, M ;

Henter, JI .

HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA, 1998, 12 (02) :435-+

[5] Upregulation of tumor necrosis factor-alpha gene by Epstein-Barr virus and activation of macrophages in Epstein-Barr virus-infected T cells in the pathogenesis of hemophagocytic syndrome [J].

Lay, JD ;

Tsao, CJ ;

Chen, JY ;

Kadin, ME ;

Su, IJ .

JOURNAL OF CLINICAL INVESTIGATION, 1997, 100 (08) :1969-1979

[6]

Papo T, 1999, J RHEUMATOL, V26, P927

[7] HEMATOPHAGIC HISTIOCYTOSIS - A REPORT OF 23 NEW PATIENTS AND A REVIEW OF THE LITERATURE [J].

REINER, AP ;

SPIVAK, JL .

MEDICINE, 1988, 67 (06) :369-388

[8] IVIG treatment of adenovirus infection-associated macrophage activation syndrome in a two-year-old boy: Case report and review of the literature [J].

Seidel, MG ;

Kastner, U ;

Minkov, M ;

Gadner, H .

PEDIATRIC HEMATOLOGY AND ONCOLOGY, 2003, 20 (06) :445-451

[9]

Sekigawa I, 2001, CLIN EXP RHEUMATOL, V19, P333

[10] THE ACUTE LUPUS HEMOPHAGOCYTIC SYNDROME [J].

WONG, KF ;

HUI, PK ;

CHAN, JKC ;

CHAN, YW ;

HA, SY .

ANNALS OF INTERNAL MEDICINE, 1991, 114 (05) :387-390

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