Drug-induced immune cytopenias

被引:41
作者
Aster, RH [1 ]
机构
[1] Med Coll Wisconsin, Milwaukee, WI 53226 USA
[2] Blood Ctr SE Wisconsin Inc, Blood Res Inst, Milwaukee, WI 53201 USA
关键词
drug-induced thrombocytopenia; immune thrombocytopenia;
D O I
10.1016/j.tox.2004.12.031
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Drugs can induce thrombocytopenia by several mechanisms, including marrow suppression and destruction of platelets in the peripheral blood by non-immune and immune mechanisms. We will review here current understanding of the immune mechanisms by which drugs promote immune-mediated platelet destruction resulting in thrombocytopenia. (c) 2005 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:149 / 153
页数:5
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