Time zones: A comparative genetics of circadian clocks

被引:908
作者
Young, MW
Kay, SA
机构
[1] Rockefeller Univ, Genet Lab, New York, NY 10021 USA
[2] Scripps Res Inst, Dept Cell Biol, La Jolla, CA 92037 USA
关键词
D O I
10.1038/35088576
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The circadian clock is a widespread cellular mechanism that underlies diverse rhythmic functions in organisms from bacteria and fungi, to plants and animals. Intense genetic analysis during recent years has uncovered many of the components and molecular mechanisms comprising these clocks. Although autoregulatory genetic networks are a consistent feature in the design of all clocks, the weight of evidence favours their independent evolutionary origins in different kingdoms.
引用
收藏
页码:702 / 715
页数:14
相关论文
共 141 条
  • [1] Reciprocal regulation between TOC1 and LHY/CCA1 within the Arabidopsis circadian clock
    Alabadí, D
    Oyama, T
    Yanovsky, MJ
    Harmon, FG
    Más, P
    Kay, SA
    [J]. SCIENCE, 2001, 293 (5531) : 880 - 883
  • [2] Stopping time: The genetics of fly and mouse circadian clocks
    Allada, R
    Emery, P
    Takahashi, JS
    Rosbash, M
    [J]. ANNUAL REVIEW OF NEUROSCIENCE, 2001, 24 : 1091 - 1119
  • [3] A mutant Drosophila homolog of mammalian Clock disrupts circadian rhythms and transcription of period and timeless
    Allada, R
    White, NE
    So, WV
    Hall, JC
    Rosbash, M
    [J]. CELL, 1998, 93 (05) : 791 - 804
  • [4] Requirement of circadian genes for cocaine sensitization in Drosophila
    Andretic, R
    Chaney, S
    Hirsh, J
    [J]. SCIENCE, 1999, 285 (5430) : 1066 - 1068
  • [5] [Anonymous], BIOCHRONOMETRY
  • [6] NEGATIVE FEEDBACK DEFINING A CIRCADIAN CLOCK - AUTOREGULATION OF THE CLOCK GENE-FREQUENCY
    ARONSON, BD
    JOHNSON, KA
    LOROS, JJ
    DUNLAP, JC
    [J]. SCIENCE, 1994, 263 (5153) : 1578 - 1584
  • [7] Circadian regulation of a Drosophila homolog of the mammalian Clock gene:: PER and TIM function as positive regulators
    Bae, K
    Lee, C
    Sidote, D
    Chuang, KY
    Edery, I
    [J]. MOLECULAR AND CELLULAR BIOLOGY, 1998, 18 (10) : 6142 - 6151
  • [8] Differential functions of mPer1, mPer2, and mPer3 in the SCN circadian clock
    Bae, K
    Jin, XW
    Maywood, ES
    Hastings, MH
    Reppert, SM
    Weaver, DR
    [J]. NEURON, 2001, 30 (02) : 525 - 536
  • [9] White collar proteins: PASsing the light signal in Neurospora crassa
    Ballario, P
    Macino, G
    [J]. TRENDS IN MICROBIOLOGY, 1997, 5 (11) : 458 - 462
  • [10] White collar-1, a central regulator of blue light responses in Neurospora, is a zinc finger protein
    Ballario, P
    Vittorioso, P
    Magrelli, A
    Talora, C
    Cabibbo, A
    Macino, G
    [J]. EMBO JOURNAL, 1996, 15 (07) : 1650 - 1657