A unifying hypothesis for the structure of microbial biofilms based on cellular automaton models

被引:257
作者
Wimpenny, JWT [1 ]
Colasanti, R [1 ]
机构
[1] UNIV SHEFFIELD,DEPT PLANT ECOL,SHEFFIELD,S YORKSHIRE,ENGLAND
关键词
cellular automaton; biofilm; colony; diffusion; model; substrate concentration;
D O I
10.1111/j.1574-6941.1997.tb00351.x
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
A review of the basic structure of microbial biofilm reveals that at least three conceptual models exist: (i) heterogeneous mosaic biofilm, (ii) penetrated water-channel biofilm and (iii) dense confluent biofilm. When consideration is given to the effects of growth resource, it may be that all three variants are correct but form at widely different substrate concentrations. Experimental research with bacterial colonies and models of the latter using cellular automata have confirmed this view. Use of cellular automata to model biofilm growth give results which strongly suggest that biofilm structure is largely determined by substrate concentration.
引用
收藏
页码:1 / 16
页数:16
相关论文
共 41 条
  • [1] [Anonymous], 1982, WHAT IS LIFE
  • [2] Barker G. C., 1993, Binary Computing in Microbiology, V5, P132
  • [3] GENERIC MODELING OF COOPERATIVE GROWTH-PATTERNS IN BACTERIAL COLONIES
    BENJACOB, E
    SCHOCHET, O
    TENENBAUM, A
    COHEN, I
    CZIROK, A
    VICSEK, T
    [J]. NATURE, 1994, 368 (6466) : 46 - 49
  • [4] METABOLIC COOPERATION IN ORAL MICROBIAL COMMUNITIES DURING GROWTH ON MUCIN
    BRADSHAW, DJ
    HOMER, KA
    MARSH, PD
    BEIGHTON, D
    [J]. MICROBIOLOGY-UK, 1994, 140 : 3407 - 3412
  • [5] IMAGING OF BACTERIAL-CELLS BY FLUORESCENCE EXCLUSION USING SCANNING CONFOCAL LASER MICROSCOPY
    CALDWELL, DE
    KORBER, DR
    LAWRENCE, JR
    [J]. JOURNAL OF MICROBIOLOGICAL METHODS, 1992, 15 (04) : 249 - 261
  • [6] Caldwell Douglas E., 1992, V12, P1
  • [7] Colasanti Ricardo L., 1992, Binary Computing in Microbiology, V4, P191
  • [8] FACTORS AFFECTING GROWTH OF BACTERIAL COLONIES ON AGAR PLATES
    COOPER, AL
    DEAN, ACR
    HINSHELWOOD, C
    [J]. PROCEEDINGS OF THE ROYAL SOCIETY SERIES B-BIOLOGICAL SCIENCES, 1968, 171 (1023): : 175 - +
  • [9] Costerton J.W., 1985, Bacterial Adhesion, P3
  • [10] BIOFILMS, THE CUSTOMIZED MICRONICHE
    COSTERTON, JW
    LEWANDOWSKI, Z
    DEBEER, D
    CALDWELL, D
    KORBER, D
    JAMES, G
    [J]. JOURNAL OF BACTERIOLOGY, 1994, 176 (08) : 2137 - 2142