Shortcomings of peer review in biomedical journals

Peer review is weil established across most academic disciplines, and publishers, editors, and researchers devote considerable resources to it. This paper uses examples from biomedical journals to examine its shortcomings. Although mainly anecdotal, the evidence suggest that peer review is sometimes ineffective at identifying important research and even less effective at detecting fraud. Most reviewers identify only the minority of a paper's defects and they may he biased. Peer review plus other editorial processes are associated with improvements in papers between submission and publication, but published papers remain hard to read and a significant proportion contain errors omissions. While it is hard to quantify the costs, peer review does not seem an efficient use of resources. Research into the "utcotries of peer review, the establishment of sound methods for measuring the quality of the process and its outcomes, and comparisons with alternative methods are needed.