Pharmacological aspects of Andrographis paniculata on health and its major diterpenoid constituent andrographolide

被引:151
作者
Jarukamjorn, Kanokwan [1 ]
Nemoto, Nobuo [2 ]
机构
[1] Khon Kaen Univ, Fac Pharmaceut Sci, Dept Pharmaceut Chem, Khon Kaen 40002, Thailand
[2] Toyama Univ, Grad Sch Med & Pharmaceut Sci, Dept Toxicol, Toyama 9300194, Japan
关键词
Andrographis paniculata; andrographolide; diterpenoid; pharmacological potential;
D O I
10.1248/jhs.54.370
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 [卫生毒理学];
摘要
Nowadays, research on medicinal plants has attracted a lot of attention globally. A number of evidence has been accumulated to demonstrate promising potential of medicinal plants used in various traditional, complementary, and alternative systems. In recent years, a medicinal plant, Andrographis paniculata, and its major active phytochemicals have been extensively studied for several pharmacological activities. To understand the mechanism of action., researches have to be carried out at molecular levels. The present review aims at compiling consequential compendium of pharmacological benefits of health on this plant and its major diterpenoid constituent andrographolide that have been tested in various experimental models using modern scientific methodologies.
引用
收藏
页码:370 / 381
页数:12
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