The first total synthesis of nakadomarin A

被引：100

作者：

Nagata, T ^{[1
]}

Nakagawa, M ^{[1
]}

Nishida, A ^{[1
]}

机构：

[1] Chiba Univ, Grad Sch Pharmaceut Sci, Inage Ku, Chiba 2638522, Japan

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2003年 / 125卷 / 25期

关键词：

D O I：

10.1021/ja034464j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(-)-Nakadomarin A is a member of manzamine alkaloid isolated from a marine sponge and have a unique hexacyclic structure. The first total synthesis of (+)-nakadomarin A, an enantiomer of natural product, has been accomplished from stereochemically defined 4-oxopiperidin-3-carboxylic acid derivative. The synthesis established the structure of nakadomarin A including absolute configuration. Copyright © 2003 American Chemical Society.

引用

页码：7484 / 7485

页数：2

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