Graft versus leukemia effect against juvenile myelomonocytic leukemia after unrelated cord blood transplantation

被引：13

作者：

Tanoshima, Reo ^{[1
]}

Goto, Hiroaki ^{[1
]}

Yanagimachi, Masakatsu ^{[1
]}

Kajiwara, Ryosuke ^{[1
]}

Kuroki, Fumiko ^{[1
]}

Yokota, Shumpei ^{[1
]}

机构：

[1] Yokohama City Univ, Dept Pediat, Kanagawa 23650004, Japan

来源：

PEDIATRIC BLOOD & CANCER | 2008年 / 50卷 / 03期

关键词：

cord blood transplantation; graft versus leukemia effect; JMML;

D O I：

10.1002/pbc.21200

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A 13-month-old female underwent unrelated cord blood transplantation (CBT) for juvenile myelomonocytic leukemia (JMML). In spite of progression of the disease after a conditioning regimen with high-dose chemotherapy, a complete remission was induced in concordance with development of acute GVHD after reduction of the immunosupressant. She has been in complete remission for 1 year after transplantation. This case illustrates that CBT can provide a potent graft versus leukemia (GVL) effect against JMML.

引用

页码：665 / 667

页数：3

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