High pressure and lanthanide catalyzed synthesis of enamino compounds

被引：22

作者：

Jenner, G

机构：

[1] Lab. de Piézochimie Organique, Synt. et Stereoreactivite, Institut de Chimie, 67008 Strasbourg

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 21期

关键词：

D O I：

10.1016/0040-4039(96)00620-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of enaminoketones from the condensation of bulky amines with ethyl acetoacetate or 2,4-pentanedione is described. The reaction can be activated either by high pressure or catalysis by ytterbium triflate. However, the pressure route is of wider applicability. The method is limited by the kinetic competition between the formation of the intermediate aminoalcohol and the dehydration step. Copyright (C) 1996 Elsevier Science Ltd.

引用

页码：3691 / 3694

页数：4

共 18 条

[1] USE OF BORON-TRIFLUORIDE ETHERATE IN THE PREPARATION OF 2-AMINO-1-ALKENYL KETONES FROM BETA-DIKETONES AND LOW-BOILING AMINES [J].