A geometry- and intensity-based partial volume correction for MRI volumetric studies

被引:8
作者
Bello, F [1 ]
Colchester, ACF [1 ]
Roll, SA [1 ]
机构
[1] Univ Kent, Kent Inst Med & Hlth Sci, Neurosci Med Image Anal Grp, Canterbury CT2 7NT, Kent, England
关键词
partial volume correction; magnetic resonance imaging; multiple sclerosis; MRI volumetric studies; lesion volume estimation;
D O I
10.1016/S0895-6111(98)00014-7
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Segmentation of objects of interest in magnetic resonance imaging is a necessary procedure for volumetric calculations. However, these direct measurements tend to be inaccurate due to the intrinsic MRI partial volume effects, In this paper, a general method for correcting these effects based on the geometry and grey level intensity of the segmented objects is presented. This method is independent of the segmentation strategy used to extract the objects of interest. An evaluation for three different segmentation methods is presented and it is shown that the proposed partial volume correction can improve the volume estimation of all three methods. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:123 / 132
页数:10
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