Transferrin variants as markers of migrations and admixture between populations in the Baltic Sea region

被引:12
作者
Beckman, L [1 ]
Sikström, C
Mikelsaar, AV
Krumina, A
Ambrasiene, D
Kucinskas, V
Beckman, G
机构
[1] Umea Univ, Dept Med Genet, S-90185 Umea, Sweden
[2] Umea Univ, Dept Clin Microbiol, S-90185 Umea, Sweden
[3] Tartu State Univ, Inst Gen & Mol Pathol, EE-202400 Tartu, Estonia
[4] Med Acad, Dept Med Biol & Genet, Riga, Latvia
[5] Vilnius State Univ, Ctr Human Genet, Vilnius, Lithuania
关键词
transferrin; migration; admixture; Baltic populations;
D O I
10.1159/000022800
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Transferrin (TF) types were examined by isoelectric focusing in an attempt to elucidate migrations and admixture between populations in the Baltic Sea region. A highly significant heterogeneity between populations was found with respect to TF*C subtypes as well as the rare TF variants B2, B0-1 and DCHI, With the exception for Estonia, increased frequencies of the TF*C3 allele were observed east of the Baltic Sea. The island of Gotland in the middle of the Baltic Sea also showed a high TF*C3 frequency indicating an eastern influence. The TF*DCHI allele, a marker of eastern (Finno-Ugric) influence, was found in Finland and Estonia and on the island of Gotland, but not in mainland Sweden and in the Baltic peoples (Latvians and Lithuanians). These results indicate the presence of a Finno-Ugric, most likely Estonian or Livonian, genetic influence in the Gotland population.
引用
收藏
页码:185 / 191
页数:7
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