The ruthenium catalyzed formation of chiral dihydropyrrolones from α,β-unsaturated imines:: extending the reaction to terminal alkenes and investigating the formation of pyrroles as side-products

被引：28

作者：

Dönnecke, D ^{[1
]}

Imhof, W ^{[1
]}

机构：

[1] Univ Jena, Inst Inorgan & Analyt Chem, D-07743 Jena, Germany

来源：

TETRAHEDRON | 2003年 / 59卷 / 43期

关键词：

catalysis; C-H activation; ruthenium; pyrrolones; pyrroles;

D O I：

10.1016/j.tet.2003.09.026

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of alpha,beta-unsaturated imines derived from cinnamaldehyde with CO and various alkenes produces chiral 1,3-dihydropyrrolone derivatives. As a byproduct the formation of 2,3-disubstituted pyrroles is observed in every reaction. If the imines are reacted with ethylene only, products with an ethyl group at C-3 of the imine chain are formed. The implications of these findings on the reaction mechanism are discussed. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：8499 / 8507

页数：9

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