Small RNAs: Keeping stem cells in line

被引:73
作者
Stadler, Bradford M. [1 ,2 ]
Ruohola-Baker, Hannele [1 ,2 ]
机构
[1] Univ Washington, Dept Biochem, Seattle, WA 98195 USA
[2] Univ Washington, Inst Stem Cell & Regenerat Med, Seattle, WA 98195 USA
关键词
D O I
10.1016/j.cell.2008.02.005
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Stem cells and RNA silencing have emerged as areas of intense interest for both basic and clinical research. Recently these fields have converged with reports implicating small regulatory RNAs in the maintenance and pluripotency of stem cells.
引用
收藏
页码:563 / 566
页数:4
相关论文
共 21 条
[1]   The Piwi-piRNA pathway provides an adaptive defense in the transposon arms race [J].
Aravin, Alexei A. ;
Hannon, Gregory J. ;
Brennecke, Julius .
SCIENCE, 2007, 318 (5851) :761-764
[2]   RNA sequence analysis defines Dicer's role in mouse embryonic stem cells [J].
Calabrese, J. Mauro ;
Seila, Amy C. ;
Yeo, Gene W. ;
Sharp, Phillip A. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (46) :18097-18102
[3]   Normal microRNA maturation and germ-line stem cell maintenance requires loquacious, a double-stranded RNA-binding domain protein [J].
Förstemann, K ;
Tomari, Y ;
Du, TT ;
Vagin, VV ;
Denli, AM ;
Bratu, DP ;
Klattenhoff, C ;
Theurkauf, WE ;
Zamore, PD .
PLOS BIOLOGY, 2005, 3 (07) :1187-1201
[4]   Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs [J].
Giraldez, AJ ;
Mishima, Y ;
Rihel, J ;
Grocock, RJ ;
Van Dongen, S ;
Inoue, K ;
Enright, AJ ;
Schier, AF .
SCIENCE, 2006, 312 (5770) :75-79
[5]   Stem cell division is regulated by the microRNA pathway [J].
Hatfield, SD ;
Shcherbata, HR ;
Fischer, KA ;
Nakahara, K ;
Carthew, RW ;
Ruohola-Baker, H .
NATURE, 2005, 435 (7044) :974-978
[6]   A role for microRNAs in maintenance of mouse mammary epithelial progenitor cells [J].
Ibarra, Ingrid ;
Erlich, Yaniv ;
Muthuswamy, Senthil K. ;
Sachidanandam, Ravi ;
Hannon, Gregory J. .
GENES & DEVELOPMENT, 2007, 21 (24) :3238-3243
[7]   Dcr-1 maintains Drosophila ovarian stem cells [J].
Jin, Zhigang ;
Xie, Ting .
CURRENT BIOLOGY, 2007, 17 (06) :539-544
[8]   Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing [J].
Kanellopoulou, C ;
Muljo, SA ;
Kung, AL ;
Ganesan, S ;
Drapkin, R ;
Jenuwein, T ;
Livingston, DM ;
Rajewsky, K .
GENES & DEVELOPMENT, 2005, 19 (04) :489-501
[9]   The diverse functions of MicroRNAs in animal development and disease [J].
Kloosterman, Wigard P. ;
Plasterk, Ronald H. A. .
DEVELOPMENTAL CELL, 2006, 11 (04) :441-450
[10]   A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans [J].
Knight, SW ;
Bass, BL .
SCIENCE, 2001, 293 (5538) :2269-2271