Revised classification/nomenclature of vitiligo and related issues: the Vitiligo Global Issues Consensus Conference

被引:449
作者
Ezzedine, K. [1 ,2 ]
Lim, H. W. [3 ]
Suzuki, T. [4 ]
Katayama, I. [5 ]
Hamzavi, I. [3 ]
Lan, C. C. E. [6 ]
Goh, B. K. [7 ]
Anbar, T. [8 ]
Silva de Castro, C. [9 ]
Lee, A. Y. [10 ]
Parsad, D. [11 ]
van Geel, N. [12 ]
Le Poole, I. C. [13 ,14 ]
Oiso, N. [15 ]
Benzekri, L. [16 ,17 ]
Spritz, R. [18 ,19 ]
Gauthier, Y. [1 ,2 ]
Hann, S. K. [20 ]
Picardo, M. [21 ]
Taieb, A. [1 ,2 ]
机构
[1] Hop Pellegrin, Natl Ctr Rare Skin Disorders, Dept Dermatol & Pediat Dermatol, F-33076 Bordeaux, France
[2] Univ Bordeaux, U1035, Bordeaux, France
[3] Henry Ford Hosp, Dept Dermatol, Detroit, MI 48202 USA
[4] Yamagata Univ, Sch Med, Dept Dermatol, Yamagata 99023, Japan
[5] Osaka Univ, Dept Dermatol, Grad Sch Med, Osaka, Japan
[6] Kaohsiung Med Univ, Dept Dermatol, Kaohsiung, Taiwan
[7] Natl Skin Ctr, Singapore 1130, Singapore
[8] Al Minya Univ, Dept Dermatol, Al Minya, Egypt
[9] Pontifical & Catholic Univ Parana, Santa Casa de Misericordia Hosp, Dept Dermatol, Curitiba, Parana, Brazil
[10] Dongguk Univ, Ilsan Hosp, Dept Dermatol, Gyeonggi Do, South Korea
[11] PGIMER, Dept Dermatol, Chandigarh, India
[12] Ghent Univ Hosp, Dept Dermatol, Ghent, Belgium
[13] Loyola Univ, Dept Pathol, Inst Oncol, Chicago, IL 60611 USA
[14] Loyola Univ, Dept Microbiol & Immunol, Inst Oncol, Chicago, IL 60611 USA
[15] Kinki Univ, Sch Med, Dept Dermatol, Osaka 589, Japan
[16] Mohammed V Souissi Univ, Rabat, Morocco
[17] Ibn Sina Univ Hosp, Dept Dermatol, Rabat, Morocco
[18] Univ Colorado Denver, Sch Med, Dept Pediat, Aurora, CO USA
[19] Univ Colorado Denver, Sch Med, Human Med Genet Program, Aurora, CO USA
[20] Drs Woo & Hanns Skin Ctr, Korea Inst Vitiligo Res, Seoul, South Korea
[21] San Gallicano Dermatol Inst, Rome, Italy
基金
美国国家卫生研究院;
关键词
vitiligo; consensus conference; SEGMENTAL VITILIGO; KOEBNERS PHENOMENON; CLINICAL-FEATURES; BASIC RESEARCH; LEUKODERMA; ETIOLOGY; SKIN; KERATINOCYTES; MANIFESTATION; ASSOCIATION;
D O I
10.1111/j.1755-148X.2012.00997.x
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
During the 2011 International Pigment Cell Conference (IPCC), the Vitiligo European Taskforce (VETF) convened a consensus conference on issues of global importance for vitiligo clinical research. As suggested by an international panel of experts, the conference focused on four topics: classification and nomenclature; definition of stable disease; definition of Koebners phenomenon (KP); and autoimmune vitiligo. These topics were discussed in seven working groups representing different geographical regions. A consensus emerged that segmental vitiligo be classified separately from all other forms of vitiligo and that the term vitiligo be used as an umbrella term for all non-segmental forms of vitiligo, including mixed vitiligo in which segmental and non-segmental vitiligo are combined and which is considered a subgroup of vitiligo. Further, the conference recommends that disease stability be best assessed based on the stability of individual lesions rather than the overall stability of the disease as the latter is difficult to define precisely and reliably. The conference also endorsed the classification of KP for vitiligo as proposed by the VETF (history based, clinical observation based, or experimentally induced). Lastly, the conference agreed that autoimmune vitiligo should not be used as a separate classification as published evidence indicates that the pathophysiology of all forms of vitiligo likely involves autoimmune or inflammatory mechanisms.
引用
收藏
页码:E1 / E13
页数:13
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