Epithelial biology:: lessons from Caenorhabditis elegans

被引：35

作者：

Michaux, G ^{[1
]}

Legouis, R ^{[1
]}

Labouesse, M ^{[1
]}

机构：

[1] Univ Strasbourg, INSERM, CNRS, Inst Genet & Biol Mol & Cellulaire, F-67000 Strasbourg, France

来源：

GENE | 2001年 / 277卷 / 1-2期

关键词：

Caenorhabditis elegans; epithelial cell; differentiation; morphogenesis; adherens junction; hemidesmosome; extracellular matrix; trafficking; cell fusion; transcription;

D O I：

10.1016/S0378-1119(01)00700-4

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Epithelial cells are essential and abundant in all multicellular animals where their dynamic cell shape changes orchestrate morphogenesis of the embryo and individual organs. Genetic analysis in the simple nematode Caenorhabditis elegans provides some clues to the mechanisms isms that are involved in specifying epithelial cell fates and in controlling specific epithelial processes such as junction assembly, trafficking or cell fusion and cell adhesion. Here we review recent findings concerning C elegans epithelial cells, focusing in particular on epithelial polarity, and transcriptional control. (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：83 / 100

页数：18

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