Von Economo neurons are present in the dorsolateral (dysgranular) prefrontal cortex of humans

被引：68

作者：

Fajardo, C. ^{[1
]}

Escobar, M. I. ^{[1
]}

Buritica, E. ^{[1
]}

Arteaga, G. ^{[1
]}

Umbarila, J. ^{[1
]}

Casanova, M. F. ^{[2
]}

Pimienta, H. ^{[1
]}

机构：

[1] Univ Valle, Fac Salud, Ctr Estudios Cerebrales, Cali, Valle, Colombia

[2] Univ Louisville, Dept Psychiat, Louisville, KY 40292 USA

来源：

NEUROSCIENCE LETTERS | 2008年 / 435卷 / 03期

关键词：

Von Economo neurons; spindle cells; anterior cingulate gyros; frontoinsular cortex; dorsolateral prefrontal cortex;

D O I：

10.1016/j.neulet.2008.02.048

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Von Economo neurons (VENs), also known as spindle cells, have been described in layer V of the anterior cingulate (BA 24) and frontoinsular cortex (FI) of humans and other great apes. In the present study we used immunohistochemistry against two specific neuronal markers (NeuN and MAP2) in order to establish the presence of these cell types in Brodmann area 9 (BA 9) of the human prefrontal cortex. We evaluated tissue samples of eight human postmortem brains (age range 26-50) from BAs 9, 24, 4, 46, 45, 10 and 17. We identified a group of cells with similar morphology to that previously described for VENs in all specimens of BA 9 examined, albeit less frequently than in BA 24. This is the first description of this cell type in a human brain area with well developed granular layers (BA 9). (c) 2008 Elsevier Ireland Ltd. All rights reserved.

引用

页码：215 / 218

页数：4

共 21 条

[1] Two phylogenetic specializations in the human brain [J].