Binding of disodium cromoglycate to human serum albumin

被引：2

作者：

de Aspuru, EO ^{[1
]}

Zaton, AML ^{[1
]}

机构：

[1] Univ Basque Country, Fac Pharm, Dept Biochem & Mol Biol, Vitoria, Spain

来源：

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY | 1998年 / 54卷 / 07期

关键词：

disodium cromoglycate; chromone binding; human serum albumin; difference spectroscopy;

D O I：

10.1016/S1386-1425(98)00056-0

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

The binding of several benzopiranone derivatives to human serum albumin was determined. The antiallergic drug disodium cromoglycate binds weakly to serum albumin. However, its precursors, chromones of smaller size; were able to bind in a hydrophobic pecker in the protein, and are carried by serum albumin in blood. (C) 1998 Elsevier Science B.V. All rights reserved.

引用

页码：983 / 988

页数：6

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