Silver Nanoparticles on a Plastic Platform for Localized Surface Plasmon Resonance Biosensing

被引：100

作者：

Fan, Meikun ^{[1
]}

Thompson, Matthew ^{[1
]}

Andrade, Maria Luiza ^{[1
]}

Brolo, Alexandre G. ^{[1
]}

机构：

[1] Univ Victoria, Dept Chem, Victoria, BC V8W 3V6, Canada

来源：

ANALYTICAL CHEMISTRY | 2010年 / 82卷 / 15期

关键词：

NANOSCALE OPTICAL BIOSENSOR; ANTIGEN-ANTIBODY REACTION; LABEL-FREE DETECTION; GOLD NANOPARTICLES; BIOMOLECULAR INTERACTIONS; COLORIMETRIC DETECTION; MOLECULAR RESONANCES; AU NANOPARTICLES; FILMS; SPECTROSCOPY;

D O I：

10.1021/ac101495m

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A cost-effective fabrication method for the preparation of localized surface plasmon resonance (LSPR) biosensors supported on plastics is described. The silver-nanoparticles-on-plastic sensor (SNOPS) was fabricated by chemically modifying the surface of a common plastic, polyethyleneterephthalate (PET) to allow the efficient immobilization of Ag NPs. The LSPR of the SNOPS strip showed good sample-to-sample reproducibility. The analytical performance of the sensor strips for monitoring both thiol and protein adsorption, including bioaffinity, was examined. The limit of quantification to the adsorption of 11-mercaptoundecanoic acid was 500 nM and for the detection of streptavidin was similar to 9.5 nM. SNOPS can then be used as a cheap, versatile, and yet sensitive LSPR biosensor.

引用

页码：6350 / 6352

页数：3

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