Concise, stereoselective approach to the spirooxindole ring system of citrinadin A

被引：62

作者：

Pettersson, Martin ^{[1
]}

Knueppel, Daniel ^{[1
]}

Martin, Stephen F. ^{[1
]}

机构：

[1] Univ Texas, Dept Chem & Biochem, Austin, TX 78712 USA

来源：

ORGANIC LETTERS | 2007年 / 9卷 / 22期

关键词：

D O I：

10.1021/ol702132v

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The spirooxindole ring system of citrinadin A has been synthesized with excellent control over the absolute stereochemistry at the spirocenter. The key step involves a novel diastereoselective DMDO-mediated oxidative rearrangement employing an 8-phenylmenthol chiral auxiliary on the indole nitrogen.

引用

页码：4623 / 4626

页数：4

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