Cancer - Cues for migration

被引:46
作者
Bernards, R
机构
[1] Netherlands Canc Inst, Div Mol Carcinogenesis, NL-1066 CX Amsterdam, Netherlands
[2] Netherlands Canc Inst, Ctr Biomed Genet, NL-1066 CX Amsterdam, Netherlands
关键词
D O I
10.1038/425247a
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Lack of oxygen causes the cells of certain tumours to spread to new locations. It also activates a homing mechanism that enables the migrating cells to target specific organs.
引用
收藏
页码:247 / 248
页数:2
相关论文
共 13 条
  • [1] Metastasis genes: A progression puzzle
    Bernards, R
    Weinberg, RA
    [J]. NATURE, 2002, 418 (6900) : 823 - 823
  • [2] Bernards R, 2002, NATURE, V419, P560, DOI 10.1038/419560b
  • [3] Cancer - Out of air is not out of action
    Bottaro, DP
    Liotta, LA
    [J]. NATURE, 2003, 423 (6940) : 593 - 595
  • [4] Chemokines:: Agents for the immunotherapy of cancer?
    Homey, B
    Müller, A
    Zlotnik, A
    [J]. NATURE REVIEWS IMMUNOLOGY, 2002, 2 (03) : 175 - 184
  • [5] Metastatic potential: Generic predisposition of the primary tumor or rare, metastatic variants - or both?
    Hynes, RO
    [J]. CELL, 2003, 113 (07) : 821 - 823
  • [6] Molecular basis of the VHL hereditary cancer syndrome
    Kaelin, WG
    [J]. NATURE REVIEWS CANCER, 2002, 2 (09) : 673 - 682
  • [7] A multigenic program mediating breast cancer metastasis to bone
    Kang, YB
    Siegel, PM
    Shu, WP
    Drobnjak, M
    Kakonen, SM
    Cordón-Cardo, C
    Guise, TA
    Massagué, J
    [J]. CANCER CELL, 2003, 3 (06) : 537 - 549
  • [8] Involvement of chemokine receptors in breast cancer metastasis
    Müller, A
    Homey, B
    Soto, H
    Ge, NF
    Catron, D
    Buchanan, ME
    McClanahan, T
    Murphy, E
    Yuan, W
    Wagner, SN
    Barrera, JL
    Mohar, A
    Verástegui, E
    Zlotnik, A
    [J]. NATURE, 2001, 410 (6824) : 50 - 56
  • [9] Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene
    Pennacchietti, S
    Michieli, P
    Galluzzo, M
    Mazzone, M
    Giordano, S
    Comoglio, PM
    [J]. CANCER CELL, 2003, 3 (04) : 347 - 361
  • [10] Vascular endothelial growth factor and basic fibroblast growth factor induce expression of CXCR4 on human endothelial cells -: In vivo neovascularization induced by stromal-derived factor-1α
    Salcedo, R
    Wasserman, K
    Young, HA
    Grimm, MC
    Howard, OMZ
    Anver, MR
    Kleinman, HK
    Murphy, WJ
    Oppenheim, JJ
    [J]. AMERICAN JOURNAL OF PATHOLOGY, 1999, 154 (04) : 1125 - 1135