Cytotoxic sterols from the soft coral Nephthea erecta

被引：58

作者：

Duh, CY ^{[1
]}

Wang, SK

Chu, MJ

Sheu, JH

机构：

[1] Natl Sun Yat Sen Univ, Dept Marine Resources, Kaohsiung 80424, Taiwan

[2] Kaohsiung Med Coll, Dept Microbiol, Kaohsiung, Taiwan

来源：

JOURNAL OF NATURAL PRODUCTS | 1998年 / 61卷 / 08期

关键词：

D O I：

10.1021/np9800497

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two new cytotoxic sterols, 24-methylcholesta-5,24(28)-diene-3 beta,15 beta, 19-triol (1) and 24-methylcholesta-5,24(28)-diene-3 beta, 19-diol-7-one (2), as well as four cytotoxic sterols, 24-methylcholesta-5,24(28)-diene-3 beta,19-diol (3), 24-methylcholesta-5,24(28)-diene-3 beta,19-diol-7 beta-mono-aetate (4), 24-methylcholesta-5,24(28)-diene-3 beta,7 beta, 19-triol(5), and 24-methylcholesta-24(28)ene-3 beta,5 alpha,6 beta,19-tetraol (6), have been isolated from the soft coral Nephthea erecta. The structures of compounds 1 and 2 were determined by spectral analysis.

引用

页码：1022 / 1024

页数：3

共 8 条

[1] Somalenone, a C-26 sterol from the marine red alga Melanothamnus somalensis [J].

Ahmad, VU ;

Memon, AH ;

Ali, MS ;

Perveen, S ;

Shameel, M .

PHYTOCHEMISTRY, 1996, 42 (04) :1141-1143

[2] CHEMICAL STUDIES OF MARINE-INVERTEBRATES .23. NOVEL POLYHYDROXYLATED STEROL FROM SOFT CORAL LITOPHYTON-VIRIDIS (COELENTERATA, OCTOCORALLIA, ALCYONACEA) [J].

BORTOLOTTO, M ;

BRAEKMAN, JC ;

DALOZE, D ;

LOSMAN, D ;

TURSCH, B .

STEROIDS, 1976, 28 (04) :461-466

[3]

GERAN RI, 1972, CANC CHEMOTHER REP, V3, P1

[4] SINUGIBBEROL, A NEW CYTOTOXIC CEMBRANOID DITERPENE FROM THE SOFT CORAL SINULARIA-GIBBEROSA [J].

HOU, RS ;

DUH, CY ;

CHIANG, MY ;

LIN, CN .

JOURNAL OF NATURAL PRODUCTS-LLOYDIA, 1995, 58 (07) :1126-1130

[5]

IGUCHI K, 1989, CHEM PHARM BULL, V37, P2553

[6]

KOBAYASHI M, 1993, CHEM PHARM BULL, V41, P87

[7] RAPID COLORIMETRIC ASSAY FOR CELLULAR GROWTH AND SURVIVAL - APPLICATION TO PROLIFERATION AND CYTO-TOXICITY ASSAYS [J].

MOSMANN, T .

JOURNAL OF IMMUNOLOGICAL METHODS, 1983, 65 (1-2) :55-63

[8]

Wang G. S., 1992, CHEM J CHINESE U, V13, P623

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