Construction of DNA architectures with RNA hairpins

被引：22

作者：

Mayer, Guenter ^{[1
]}

Ackermann, Damian ^{[1
]}

Kuhn, Nicole ^{[1
]}

Famulok, Michael ^{[1
]}

机构：

[1] Univ Bonn, LIMES Life & Med Sci Inst, Programmeinheit Chem Biol & Med Chem, D-53121 Bonn, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 05期

关键词：

DNA structures; hairpins; nanostructures; RNA structures; self-assembly;

D O I：

10.1002/anie.200704709

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Kissing complexes formed on the basis of highly specific noncanonical interactions of RNA hairpins can be harnessed for the controlled assembly of DNA nanoobjects. Two DNA minicircles, each equipped with a different RNA hairpin motif (see picture), mediate a tight and specific binding of the two circular DNA nanoobjects. These interactions may offer the possibility to construct DNA nanoobjects with increased complexity. (Chemical Equation Presented). © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：971 / 973

页数：3

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