The Use of Electrospun Organic and Carbon Nanofibers in Bone Regeneration

被引:32
作者
Aoki, Kaoru [1 ]
Haniu, Hisao [2 ,3 ]
Kim, Yoong Ahm [4 ]
Saito, Naoto [2 ]
机构
[1] Shinshu Univ, Sch Hlth Sci, Phys Therapy Div, 3-1-1 Asahi, Matsumoto, Nagano 3908621, Japan
[2] Shinshu Univ, Inst Biomed Sci, Interdisciplinary Cluster Cutting Edge Res, 3-1-1 Asahi, Matsumoto, Nagano 3908621, Japan
[3] Shinshu Univ, Grad Sch Med Sci & Technol, Dept Biomed Engn, 3-1-1 Asahi, Matsumoto, Nagano 3908621, Japan
[4] Chonnam Natl Univ, Alan G MacDiarmid Energy Res Inst, Dept Polymer Engn, 77 Yongbong Ro, Gwangju 61186, South Korea
关键词
bone defects; scaffolds; electrospinning; bone regeneration; electrospun nanofibers; INDUCED MEMBRANE TECHNIQUE; OSTEOGENIC DIFFERENTIATION; MASSIVE ALLOGRAFT; ILIAC CREST; STEM-CELLS; SCAFFOLD; COLLAGEN; POLYMER; REPAIR; RECONSTRUCTION;
D O I
10.3390/nano10030562
中图分类号
O6 [化学];
学科分类号
070301 [无机化学];
摘要
There has been an increasing amount of research on regenerative medicine for the treatment of bone defects. Scaffolds are needed for the formation of new bone, and various scaffolding materials have been evaluated for bone regeneration. Materials with pores that allow cells to differentiate into osteocytes are preferred in scaffolds for bone regeneration, and porous materials and fibers are well suited for this application. Electrospinning is an effective method for producing a nanosized fiber by applying a high voltage to the needle tip containing a polymer solution. The use of electrospun nanofibers is being studied in the medical field, and its use as a scaffold for bone regeneration therapy has become a topic of growing interest. In this review, we will introduce the potential use of electrospun nanofiber as a scaffold for bone regenerative medicine with a focus on carbon nanofibers produced by the electrospinning method.
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页数:14
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