Sperm mitochondrial DNA deletions as a consequence of long term highly active antiretroviral therapy

被引:41
作者
White, DJ [1 ]
Mital, D
Taylor, S
St John, JC
机构
[1] Birmingham Heartlands Hosp, Dept Infect, Birmingham B9 5ST, W Midlands, England
[2] Univ Birmingham, Dept Med, Reprod Biol & Genet Grp, Birmingham, W Midlands, England
关键词
D O I
10.1097/00002030-200105250-00017
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
[No abstract available]
引用
收藏
页码:1061 / 1062
页数:2
相关论文
共 17 条
[1]   DEPLETION OF MUSCLE MITOCHONDRIAL-DNA IN AIDS PATIENTS WITH ZIDOVUDINE-INDUCED MYOPATHY [J].
ARNAUDO, E ;
DALAKAS, M ;
SHANSKE, S ;
MORAES, CT ;
DIMAURO, S ;
SCHON, EA .
LANCET, 1991, 337 (8740) :508-510
[2]   Mitochondrial toxicity induced by nucleoside-analogue reverse-transcriptase inhibitors is a key factor in the pathogenesis of antiretroviral-therapy-related lipodystrophy [J].
Brinkman, K ;
Smeitink, JA ;
Romijn, JA ;
Reiss, P .
LANCET, 1999, 354 (9184) :1112-1115
[3]  
CHEN CH, 1991, MOL PHARMACOL, V39, P625
[4]   Subcutaneous adipocyte apoptosis in HIV-1 protease inhibitor-associated lipodystrophy [J].
Domingo, P ;
Matias-Guiu, X ;
Pujol, RM ;
Francia, E ;
Lagarda, E ;
Sambeat, MA ;
Vázquez, G .
AIDS, 1999, 13 (16) :2261-2267
[5]   A receptor for phosphatidylserine-specific clearance of apoptotic cells [J].
Fadok, VA ;
Bratton, DL ;
Rose, DM ;
Pearson, A ;
Ezekewitz, RAB ;
Henson, PM .
NATURE, 2000, 405 (6782) :85-90
[6]   Detection of mitochondrial DNA deletions by a screening procedure using the polymerase chain reaction [J].
Ferlin, T ;
Guironnet, G ;
Barnoux, MC ;
Dumoulin, R ;
Stepien, G ;
Mousson, B .
MOLECULAR AND CELLULAR BIOCHEMISTRY, 1997, 174 (1-2) :221-225
[7]  
GAZZARD BG, 1999, BHIVA GUIDELINES
[8]   MASSIVE CONVERSION OF GUANOSINE TO 8-HYDROXY-GUANOSINE IN MOUSE-LIVER MITOCHONDRIAL-DNA BY ADMINISTRATION OF AZIDOTHYMIDINE [J].
HAYAKAWA, M ;
OGAWA, T ;
SUGIYAMA, S ;
TANAKA, M ;
OZAWA, T .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1991, 176 (01) :87-93
[9]  
Hermo L., 1995, P13
[10]   Multiple deletions of mitochondrial DNA are associated with the decline of motility and fertility of human spermatozoa [J].
Kao, SH ;
Chao, HT ;
Wei, YH .
MOLECULAR HUMAN REPRODUCTION, 1998, 4 (07) :657-666