Mitogen activated protein kinases (MAPKs) as regulators of spermatogenesis and spermatozoa functions

被引:81
作者
Almog, Tal [1 ]
Naor, Zvi [1 ]
机构
[1] Tel Aviv Univ, George S Wise Fac Life Sci, Dept Biochem, IL-69978 Ramat Aviv, Israel
关键词
MAPK; spermatozoa; ERK; spermatogenesis;
D O I
10.1016/j.mce.2007.11.011
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Spermatogenesis, culminating in the generation of mature motile spermatozoa, is a complex biological process that is regulated by cytokines and hormones of the male reproductive system. Spermatozoa must first undergo a series of biochemical processes termed capacitation, which is followed by acrosome reaction and egg fertilization. Here we review the role of mitogen-activated protein kinases (MAPK) cascades in spermatogenesis and spermatozoa functions. (c) 2007 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:39 / 44
页数:6
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