'Ins' and 'outs' of triple therapy Optimal antiplatelet therapy in patients on chronic oral anticoagulation who need coronary stenting

被引：3

作者：

Dewilde, W. ^{[1
]}

Verheugt, F. W. A. ^{[3
]}

Breet, N. ^{[4
]}

Koolen, J. J. ^{[2
]}

Ten Berg, J. M. ^{[4
]}

机构：

[1] TweeSteden Hosp Tilburg, NL-5000 LA Tilburg, Netherlands

[2] Catharina Hosp, Eindhoven, Netherlands

[3] Onze Lieve Vrouw Hosp, Dept Cardiol, Amsterdam, Netherlands

[4] St Antonius Hosp, Nieuwegein, Netherlands

来源：

NETHERLANDS HEART JOURNAL | 2010年 / 18卷 / 09期

关键词：

Atrial Fibrillation; Triple Therapy; Dual Antiplatelet Therapy; Percutaneous Coronary Intervention; Mechanical Valves; Oral Anticoagulation; ELEVATION MYOCARDIAL-INFARCTION; ASSOCIATION TASK-FORCE; ANTITHROMBOTIC THERAPY; BLEEDING COMPLICATIONS; ATRIAL-FIBRILLATION; AMERICAN-COLLEGE; CLOPIDOGREL; WARFARIN; ASPIRIN; INTERVENTION;

D O I：

10.1007/BF03091812

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Chronic oral anticoagulant treatment is obligatory in patients (class I) with mechanical heart valves and in patients with atrial fibrillation with CHADS2 score >1. When these patients undergo percutaneous coronary intervention with placement of a stent, there is also an indication for treatment with aspirin and clopidogrel. Unfortunately, triple therapy is known to increase the bleeding risk. For this group of patients, the bottom line is to find the ideal therapy in patients with indications for both chronic anticoagulation therapy and percutaneous intervention to prevent thromboembolic complications such as stent thrombosis without increasing the risk of bleeding. (Neth Heart J 2010;18:444-50.)

引用

页码：444 / 450

页数：7

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