Investigation of Magnesium Incorporation within Gelatin/Calcium Phosphate Nanocomposite Scaffold for Bone Tissue Engineering

被引：21

作者：

Baheiraei, Nafiseh ^{[1
]}

Azami, Mahmoud ^{[1
]}

Hosseinkhani, Hossein ^{[2
]}

机构：

[1] Univ Tehran Med Sci, Sch Adv Technol Med, Dept Tissue Engn, Tehran 1417755469, Iran

[2] Natl Taiwan Univ Sci & Technol, Grad Inst Biomed Engn, Taipei, Taiwan

来源：

INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY | 2015年 / 12卷 / 02期

关键词：

AMORPHOUS CALCIUM-PHOSPHATE; IN-VITRO SYNTHESIS; CHITOSAN MEMBRANE; APATITE FORMATION; CRYSTAL-GROWTH; HYDROXYAPATITE; MINERALIZATION; COMPOSITES; BIOMINERALIZATION; TITANIUM;

D O I：

10.1111/ijac.12189

中图分类号：

TQ174 [陶瓷工业]; TB3 [工程材料学];

学科分类号：

081705 [工业催化]; 082905 [生物质能源与材料];

摘要：

In this study, diffusional method was used to prepare a calcium phosphate/gelatin nanocomposite as a scaffold for bone tissue repair. Incorporation of magnesium (Mg) into mineral phase of the scaffold was also investigated. Addition of Mg ions to the synthesis process caused formation of magnesium phosphate (MgP) and hydroxyapatite (HAp). However, analyses data for the sample lacking Mg showed that the mineral formed within GEL had a low crystalline nature, consisting of HAp and octacalcium phosphate (OCP). With addition of Mg within the structure of precipitated minerals, morphology of minerals was dramatically changed toward being irregular and less ordered.

引用

页码：245 / 253

页数：9

共 49 条

[1]

Preparation of a biomimetic nanocomposite scaffold for bone tissue engineering via mineralization of gelatin hydrogel and study of mineral transformation in simulated body fluid [J].