C-terminal PEG blocks the irreversible step in β-amyloid(10-35) fibrillogenesis

被引：124

作者：

Burkoth, TS

Benzinger, TLS

Jones, DNM

Hallenga, K

Meredith, SC

Lynn, DG

机构：

[1] Univ Chicago, Dept Pathol, Chicago, IL 60637 USA

[2] Univ Chicago, Dept Chem, Chicago, IL 60637 USA

[3] Univ Chicago, Dept Radiol, Chicago, IL 60637 USA

[4] Univ Chicago, Dept Biochem & Mol Biol, Chicago, IL 60637 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1998年 / 120卷 / 30期

关键词：

D O I：

10.1021/ja980566b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

[No abstract available]

引用

页码：7655 / 7656

页数：2

共 30 条

[1]

Bayer E., 1992, POLYETHYLENE GLYCOL, P325

[2]

BENZINGER TLS, UNPUB

[3]

BURDICK D, 1992, J BIOL CHEM, V267, P546

[4] INVITRO FORMATION OF AMYLOID FIBRILS FROM 2 SYNTHETIC PEPTIDES OF DIFFERENT LENGTHS HOMOLOGOUS TO ALZHEIMERS-DISEASE BETA-PROTEIN [J].

CASTANO, EM ;

GHISO, J ;

PRELLI, F ;

GOREVIC, PD ;

MIGHELI, A ;

FRANGIONE, B .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1986, 141 (02) :782-789

[5] TRANSGLUTAMINASE FACILITATES THE FORMATION OF POLYMERS OF THE BETA-AMYLOID PEPTIDE [J].

DUDEK, SM ;

JOHNSON, GVW .

BRAIN RESEARCH, 1994, 651 (1-2) :129-133

[6] Point substitution in the central hydrophobic cluster of a human beta-amyloid congener disrupts peptide folding and abolishes plaque competence [J].

Esler, WP ;

Stimson, ER ;

Ghilardi, JR ;

Lu, YA ;

Felix, AM ;

Vinters, HV ;

Mantyh, PW ;

Lee, JP ;

Maggio, JE .

BIOCHEMISTRY, 1996, 35 (44) :13914-13921

[7] PH-DEPENDENT STRUCTURAL TRANSITIONS OF ALZHEIMER AMYLOID PEPTIDES [J].

FRASER, PE ;

NGUYEN, JT ;

SUREWICZ, WK ;

KIRSCHNER, DA .

BIOPHYSICAL JOURNAL, 1991, 60 (05) :1190-1201

[8] ALZHEIMERS-DISEASE AND DOWNS-SYNDROME - SHARING OF A UNIQUE CEREBROVASCULAR AMYLOID FIBRIL PROTEIN [J].

GLENNER, GG ;

WONG, CW .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1984, 122 (03) :1131-1135

[9] CHARACTERIZATION AND CHROMOSOMAL LOCALIZATION OF A CDNA-ENCODING BRAIN AMYLOID OF ALZHEIMERS-DISEASE [J].

GOLDGABER, D ;

LERMAN, MI ;

MCBRIDE, OW ;

SAFFIOTTI, U ;

GAJDUSEK, DC .

SCIENCE, 1987, 235 (4791) :877-880

[10] MOLECULAR DETERMINANTS OF AMYLOID DEPOSITION IN ALZHEIMERS-DISEASE - CONFORMATIONAL STUDIES OF SYNTHETIC BETA-PROTEIN FRAGMENTS [J].

HALVERSON, K ;

FRASER, PE ;

KIRSCHNER, DA ;

LANSBURY, PT .

BIOCHEMISTRY, 1990, 29 (11) :2639-2644

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