ArrayCyGHt: a web application for analysis and visualization of array-CGH data

被引:29
作者
Kim, SY
Nam, SW
Lee, SH
Park, WS
Yoo, NJ
Lee, JY
Chung, YJ [1 ]
机构
[1] Catholic Univ Korea, Coll Med, Dept Microbiol, Seoul 137701, South Korea
[2] Catholic Univ Korea, Coll Med, Microdissect Genom Res Ctr, Seoul 137701, South Korea
[3] Catholic Univ Korea, Coll Med, Dept Pathol, Seoul 137701, South Korea
关键词
D O I
10.1093/bioinformatics/bti357
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
ArrayCyGHt is a web-based application tool for analysis and visualization of microarray-comparative genomic hybridization (array-CGH) data. Full process of array-CGH data analysis, from normalization of raw data to the final visualization of copy number gain or loss, can be straightforwardly achieved on this arrayCyGHt system without the use of any further software. ArrayCyGHt, therefore, provides an easy and fast tool for the analysis of copy number aberrations in any kinds of data format.
引用
收藏
页码:2554 / 2555
页数:2
相关论文
共 7 条
[1]   Analysis of array CGH data:: from signal ratio to gain and loss of DNA regions [J].
Hupé, P ;
Stransky, N ;
Thiery, JP ;
Radvanyi, F ;
Barillot, E .
BIOINFORMATICS, 2004, 20 (18) :3413-3422
[2]   Fully automatic quantification of microarray image data [J].
Jain, AN ;
Tokuyasu, TA ;
Snijders, AM ;
Segraves, R ;
Albertson, DG ;
Pinkel, D .
GENOME RESEARCH, 2002, 12 (02) :325-332
[3]   Breakpoint identification and smoothing of array comparative genomic hybridization data [J].
Jong, K ;
Marchiori, E ;
Meijer, G ;
Van der Vaart, A ;
Ylstra, B .
BIOINFORMATICS, 2004, 20 (18) :3636-3637
[4]   CGH-Explorer:: a program for analysis of array-CGH data [J].
Lingjærde, OC ;
Baumbusch, LO ;
Liestol, K ;
Glad, IK ;
Borresen-Dale, AL .
BIOINFORMATICS, 2005, 21 (06) :821-822
[5]   High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays [J].
Pinkel, D ;
Seagraves, R ;
Sudar, D ;
Clark, S ;
Poole, I ;
Kowbel, D ;
Collins, C ;
Kuo, WL ;
Chen, C ;
Zhai, Y ;
Dairkee, SH ;
Ljung, BM ;
Gray, JW ;
Albertson, DG .
NATURE GENETICS, 1998, 20 (02) :207-211
[6]  
Smyth G. K., 2004, Stat. Appl. Genet. Mol. Biol., V3, P1, DOI DOI 10.2202/1544-6115.1027
[7]   Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation [J].
Yang, YH ;
Dudoit, S ;
Luu, P ;
Lin, DM ;
Peng, V ;
Ngai, J ;
Speed, TP .
NUCLEIC ACIDS RESEARCH, 2002, 30 (04) :e15