New tools and expanded data analysis capabilities at the protein structure prediction center

被引:18
作者
Kryshtafovych, Andriy
Prlic, Andreas
Dmytriv, Zinoviy
Daniluk, Pawel
Milostan, Maciej
Eyrich, Volker
Hubbard, Tim
Fidelis, Krzysztof
机构
[1] Univ Calif Davis, Genome Ctr, Davis, CA 95616 USA
[2] Sanger Ctr, Hinxton CB10 1SA, Cambs, England
[3] Poznan Univ Tech, Inst Comp Sci, PL-60965 Poznan, Poland
[4] Columbia Univ, Dept Biochem & Mol Biophys, CUBIC, New York, NY 10032 USA
基金
英国惠康基金;
关键词
CASP infrastructure; protein structure prediction; evaluation methods; SPICE;
D O I
10.1002/prot.21653
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
We outline the main tasks performed by the Protein Structure Prediction Center in support of the CASP7 experiment and provide a brief review of the major measures used in the automatic evaluation of predictions. We describe in more detail the software developed to facilitate analysis of modeling success over and beyond the available templates and the adopted Java-based tool enabling visualization of multiple structural superpositions between target and several models/templates. We also give an overview of the CASP infrastructure provided by the Center and discuss the organization of the results web pages available through http:// predictioncenter.org.
引用
收藏
页码:19 / 26
页数:8
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