Response of Drosophila metallothionein promoters to metallic, heat shock and oxidative stresses

被引：38

作者：

Bonneton, F

Theodore, L

Silar, P

Maroni, G

Wegnez, M

机构：

[1] UNIV PARIS 11, CNRS, URA 1134, LAB EMBRYOL MOLEC & EXPTL, F-91405 ORSAY, FRANCE

[2] UNIV N CAROLINA, DEPT BIOL, CHAPEL HILL, NC 27599 USA

来源：

FEBS LETTERS | 1996年 / 380卷 / 1-2期

关键词：

metallothionein; metal intoxication; heat-shock; oxidative stress; Drosophila melanogaster;

D O I：

10.1016/0014-5793(95)01544-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The metallothionein system in Drosophila melanogaster is composed of two genes, Mtn and Mto, In order to compare the induction properties of these genes, we transformed D. melanogaster with P-element vectors containing Adh and lacZ reporter genes under the control of Mtn and Mto promoters, respectively, Mtn and Mto transgenes are mainly expressed in the digestive tract, However, Mtn expression has been detected also in the fat body, Mtn and Mto transgenes respond differently to metallic, heat-shock and oxidative stresses, These data confirm that both genes are in part functionally different.

引用

页码：33 / 38

页数：6

共 32 条

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ASHBURNER M, 1989, DROSOPHILA LABORATOR

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