Dyslipidaemia in adult growth hormone (GH) deficiency and the effect of GH replacement therapy: A review

被引：20

作者：

Christ, ER ^{[1
]}

Cummings, MH ^{[1
]}

Russell-Jones, DL ^{[1
]}

机构：

[1] United Med & Dent Sch Guys & St Thomas Hosp, St Thomas Hosp, Dept Med, London SE1 7EH, England

来源：

TRENDS IN ENDOCRINOLOGY AND METABOLISM | 1998年 / 9卷 / 05期

关键词：

D O I：

10.1016/S1043-2760(98)00050-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Adult growth hormone (GH) deficiency is associated with a lipid profile known to be related to atherosclerosis. GH replacement therapy improves the lipid profile with the exception of lipoprotein (a) concentrations, which tend to increase after GH therapy. Plasma lipid concentrations depend on its plasma carriers, the lipoproteins. Possible mechanisms involved in the dyslipidaemia of GH-deficient patients and the effects of GH replacement therapy are discussed with a special focus on hepatic lipoprotein metabolism.

引用

页码：200 / 206

页数：7

共 61 条

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