Developmental expression of the cell adhesion molecule-like protein tyrosine phosphatases LAR, RPTPδ and RPTPσ in the mouse

被引：61

作者：

Schaapveld, RQJ

Schepens, JTG

Bächner, D

Attema, J

Wieringa, B

Jap, PHK

Hendriks, WJAJ

机构：

[1] Univ Nijmegen, Inst Cellular Signalling, Dept Histol & Cell Biol, NL-6525 EK Nijmegen, Netherlands

[2] Univ Hamburg, Hosp Eppendorf, Inst Cellular Biochem, D-20529 Hamburg, Germany

来源：

MECHANISMS OF DEVELOPMENT | 1998年 / 77卷 / 01期

关键词：

cell adhesion molecule; RPTPase family; mouse development; basal lamina; spatio-temporal expression;

D O I：

10.1016/S0925-4773(98)00119-1

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Using RNA in situ hybridization we compared the expression patterns of the cell adhesion molecule-like receptor-type protein tyrosine phosphatases LAR, RPTP delta and RPTP delta during mouse development. We found that LAR is expressed in basal lamina-associated epithelial tissues of (neuro)ectodermal, neural crest/ectomesenchyme and endodermal origin. RPTP sigma is found in (neuro)ectodermal, neural crest-derived systems and in mesoderm-derived tissues. The expression pattern of RPTP sigma largely parallels that of RPTP sigma, in concordance with their proposed evolutionary history (Schaapveld ct al., 1995). (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：59 / 62

页数：4

共 19 条

[1] Cellular redistribution of protein tyrosine phosphatases LAR and PTP sigma by inducible proteolytic processing [J].