Interplay of innate lymphoid cells and the microbiota

被引：54

作者：

Britanova, Liudmila ^{[1
,2
]}

Diefenbach, Andreas ^{[3
,4
]}

机构：

[1] Res Ctr Immunotherapy, Mainz, Germany

[2] Inst Microbiol & Hyg, Mainz, Germany

[3] Charite, Dept Microbiol, Berlin, Germany

[4] Berlin Inst Hlth, Berlin, Germany

来源：

IMMUNOLOGICAL REVIEWS | 2017年 / 279卷 / 01期

基金：

欧洲研究理事会;

关键词：

innate lymphoid cells; microbiota; NK cells; ARYL-HYDROCARBON RECEPTOR; ROR-GAMMA-T; NATURAL-KILLER-CELLS; TRANSCRIPTION FACTOR BCL11B; COMMENSAL BACTERIA; TISSUE HOMEOSTASIS; TYPE-2; IMMUNITY; GUT MICROBIOTA; HOST-DEFENSE; NK CELLS;

D O I：

10.1111/imr.12580

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

071005 [微生物学]; 100108 [医学免疫学];

摘要：

Innate lymphoid cells (ILC) are a recently identified group of innate lymphocytes that are preferentially located at barrier surfaces. Barrier surfaces are in direct contact with complex microbial ecosystems, collectively referred to as the microbiota. It is now believed that the interplay of the microbiota with host components (i.e. epithelial cells and immune cells) promotes host fitness by regulating organ homeostasis, metabolism, and host defense against pathogens. In this review, we will give an overview of this multifaceted interplay between ILC and components of the microbiota.

引用

页码：36 / 51

页数：16

共 204 条

[1]

Commensal Bacteria Calibrate the Activation Threshold of Innate Antiviral Immunity [J].

Abt, Michael C. ;

Osborne, Lisa C. ;

Monticelli, Laurel A. ;

Doering, Travis A. ;

Alenghat, Theresa ;

Sonnenberg, Gregory F. ;

Paley, Michael A. ;

Antenus, Marcelo ;

Williams, Katie L. ;

Erikson, Jan ;

Wherry, E. John ;

Artis, David .

IMMUNITY, 2012, 37 (01) :158-170

[2]

[Anonymous], 2015, IMMUNITY, DOI DOI 10.1016/J.IMMUNI.2015.06.006

[3]

IL-1β, IL-4 and IL-12 control the fate of group 2 innate lymphoid cells in human airway inflammation in the lungs [J].

Bal, Suzanne M. ;

Bernink, Jochem H. ;

Nagasawa, Maho ;

Groot, Jelle ;

Shikhagaie, Medya M. ;

Golebski, Kornel ;

van Drunen, Cornelis M. ;

Lutter, Rene ;

Jonkers, Rene E. ;

Hombrink, Pleun ;

Bruchard, Melanie ;

Villaudy, Julien ;

Munneke, J. Marius ;

Fokkens, Wytske ;

Erjefalt, Jonas S. ;

Spits, Hergen ;

Ros, Xavier Romero .

NATURE IMMUNOLOGY, 2016, 17 (06) :636-+

[4]

Innate lymphoid cell function in the context of adaptive immunity [J].

Bando, Jennifer K. ;

Colonna, Marco .

NATURE IMMUNOLOGY, 2016, 17 (07) :783-789

[5]

Lipoxin A4 Regulates Natural Killer Cell and Type 2 Innate Lymphoid Cell Activation in Asthma [J].

Barnig, Cindy ;

Cernadas, Manuela ;

Dutile, Stefanie ;

Liu, Xiaoli ;

Perrella, Mark A. ;

Kazani, Shamsah ;

Wechsler, Michael E. ;

Israel, Elliot ;

Levy, Bruce D. .

SCIENCE TRANSLATIONAL MEDICINE, 2013, 5 (174)

[6]

Antimicrobial Proteins and Peptides in early Life: Ontogeny and Translational Opportunities [J].

Battersby, Anna J. ;

Khara, Jasmeet ;

Wright, Victoria J. ;

Levy, Ofer ;

Kampmann, Beate .

FRONTIERS IN IMMUNOLOGY, 2016, 7

[7]

Inflammation-induced formation of fat-associated lymphoid clusters [J].

Benezech, Cecile ;

Luu, Nguyet-Thin ;

Walker, Jennifer A. ;

Kruglov, Andrei A. ;

Loo, Yunhua ;

Nakamura, Kyoko ;

Zhang, Yang ;

Nayar, Saba ;

Jones, Lucy H. ;

Flores-Langarica, Adriana ;

McIntosh, Alistair ;

Marshall, Jennifer ;

Barone, Francesca ;

Besra, Gurdyal ;

Miles, Katherine ;

Allen, Judith E. ;

Gray, Mohini ;

Kollias, George ;

Cunningham, Adam F. ;

Withers, David R. ;

Toellner, Kai Michael ;

Jones, Nick D. ;

Veldhoen, Marc ;

Nedospasov, Sergei A. ;

McKenzie, Andrew N. J. ;

Caamano, Jorge H. .

NATURE IMMUNOLOGY, 2015, 16 (08) :819-+

[8]

Eosinophils: important players in humoral immunity [J].

Berek, C. .

CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2016, 183 (01) :57-64

[9]

Interleukin-12 and-23 Control Plasticity of CD127+ Group 1 and Group 3 Innate Lymphoid Cells in the Intestinal Lamina Propria [J].

Bernink, Jochem H. ;

Krabbendam, Lisette ;

Germar, Kristine ;

de Jong, Esther ;

Gronke, Konrad ;

Kofoed-Nielsen, Michael ;

Munneke, J. Marius ;

Hazenberg, Mette D. ;

Villaudy, Julien ;

Buskens, Christianne J. ;

Bemelman, Willem A. ;

Diefenbach, Andreas ;

Blom, Bianca ;

Spits, Hergen .

IMMUNITY, 2015, 43 (01) :146-160

[10]

Normalizing Microbiota-Induced Retinoic Acid Deficiency Stimulates Protective CD8+ T Cell-Mediated Immunity in Colorectal Cancer [J].

Bhattacharya, Nupur ;

Yuan, Robert ;

Prestwood, Tyler R. ;

Penny, Hweixian Leong ;

DiMaio, Michael A. ;

Reticker-Flynn, Nathan E. ;

Krois, Charles R. ;

Kenkel, Justin A. ;

Pham, Tho D. ;

Carmi, Yaron ;

Tolentino, Lorna ;

Choi, Okmi ;

Hulett, Reyna ;

Wang, Jinshan ;

Winer, Daniel A. ;

Napoli, Joseph L. ;

Engleman, Edgar G. .

IMMUNITY, 2016, 45 (03) :641-655

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